In the early-to-mid 1900s, the rates of stroke & heart attacks were on the rise.
Smoking was a known contributor to this phenomenon. It is a dense source of oxidative stress. When you take your first puff of cigarette smoke, it feels like your chest is on fire. In more ways than one, it is.
Oxidation reactions there needs fuel. So, if smoking is providing oxidative stress...then what is the fuel?
Unfortunately for us, there was a second culprit blamed for the rise of cardiovascular disease - saturated fats. That is the topic of this article.
Fire & Mitochondria
Before we continue with the danger to the circulatory system, we need to take a brief detour to discuss the relationship between fire and metabolism.
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Read the whole article
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The evidence is overwhelming (experimental and clinical) that oxidation of PUFAs play a role in every step of atherosclerosis, including fatty streak formation, atheromatous lesion, plaque instability and rupture. Instability & rupture causes strokes in the brain, heart attacks, and infarctions in every organ that has limited blood supply. The liver and skin are less impacted - they have a lot of redundant blood supply, and usually the other critical organs fail first (e.g brain, heart, kidneys).
The above diagrammed chain reaction is the reason why PUFAs are so dangerous.
Recall the description of combustion:
The combustion of fuel occurs in the absence of enzymes, and relies on a chain reaction to propagate itself until the fuel or oxygen has been consumed.
Lipid peroxidation chain reactions will continue until one radical encounters another radical, neutralizing one another.
Now, imagine that the cells which line your blood vessel (endothelium) have PUFAs in their membranes. The red blood cell membranes also have PUFAs. The balls of cholesterol floating in your blood stream have PUFAs. They are all waiting for an oxidation event.
Oxidation-reduction reactions are the norm throughout the body. But in the presence of PUFAs, this can lead to chain reactions that can propagate uncontrolled. Whether it's the inner wall of the blood vessel, or a ball of cholesterol rushing towards your brain.
The endothelium (blood vessel lining) is a very sensitive single-layer membrane that comes in direct contact with the contents of blood. Even a microsecond of a PUFA oxidation event can damage it, exposing the layers underneath. Once these layers are exposed, one of two things can happen which are potentially devastating:
- Other reactive fatty acids (more PUFAs, for example) can bind to it. This results in fatty streak formation, and eventual atherosclerosis.
- Platelets can start binding and aggregating to exposed basement membrane proteins. This can lead to clot formation ⇨ infarcts
This is why ulcerated atherosclerotic plaques are predictive of impending stroke, heart attack, or dissection. In my estimation, this mechanism also plays a role in aneurysm rupture.
Death by a Thousand Cuts
If the damage caused by these PUFAs was a brief episode, you probably wouldn't suffer long-term illness.
But, many people who consume PUFAs do so for years and decades, if not their whole life. You can hardly blame them - seed oils are in almost everything we consume. In fact, people who try to avoid seed oils often have a hard time both in restaurants and the grocery store. It is so widespread, it has likely contributed to the recent trend of extreme elimination diets.
These elimination diets have a point.
Lipid peroxidation and highly inflammatory states contribute to almost everything that's causing illness in the modern world:
- Cardiovascular disease (leading cause of death and disability)
- Cancer
- Dementia
- Kidney Failure
- Autoimmunity
- Even Osteoporosis ⇨ fractures, which is often categorized as traumatic
As a little experiment, go to a search engine and query:
"Lipid peroxidation" and "any chronic illness"
Every tissue needs blood perfusion. By slowly destroying the blood supply, you develop micro-infarcts that accumulate across time. And, by delivering highly reactive PUFAs to an organ, you are actively oxidizing it. It's lose-lose.
Brain MRI demonstrating grade of 'microvascular ischemia' - tiny infarcts that manifest as confluent loss of white matter across time
Connection to COVID
There are two connections to COVID, actually.
The first is reasonably well encapsulated in this tweet:
I believe the abnormally high rates of illness this past 2 years is due to:
1. Lockdowns/restrictions and the downstream health consequences
2. Inflation causing people to shift towards more affordable food (seed oil, cheap carbs)
3. Global-scale clinical trialNo one virus.
— Remnant | MD (@RemnantMd) April 17, 2022
When the lockdown and restrictions started to get really heavy-handed, reasonable people were concerned with the behavioral changes that would be harmful:
- More sedentary life
- Ordering food (for many reasons, including supporting local businesses)
- Increased alcohol and drug use
This is one connection to the "COVID era," and we are now seeing the consequences of these behaviors. I know some people want to blame the differences in rates of illness to the vaccines, but I think that is only one of three contributing factors.
Revisiting Oxidation
The second connection is directly related to oxidative stress.
Our lungs help bring oxygen into the bloodstream, so that it can be circulated to our organs. Oxygen is just one oxidant in the air. There's also ozone, amongst others. Our lungs are constantly exposed to oxidative stress - especially if you are a smoker.
You would think that our lungs have evolved mechanisms to resist oxidants - and they have! For example, surfactant (the fluid that keeps your lungs open) has a protein which binds to and neutralizes oxidants. But, even the lungs have their limit. At some point, they will give in. What happens when the lungs fail?
The lungs provide a boundary that allows your blood to engage with the air without letting free air into your blood stream, or fluid moving into your lungs. So when the lung fails...fluid tends to accumulate in the lungs.
Acute Respiratory Distress Syndrome
ARDS is a type of respiratory failure characterized by rapid onset of widespread inflammation in the lungs - leading to fluid build-up.
Obesity is a risk factor for ARDS. It also happens to be a major risk factor for severe COVID-19. One mechanism accounting for this is that people who are obese tend to have a diet high in PUFAs. PUFAs stored in fat can be oxidized as part of a chain reaction, which will lead to a higher severity/amplitude of inflammation.
In the early days of COVID, people were admitted left and right with what looked like ARDS. Our central medical authorities decided this was 'severe COVID.'
But, if you take an unhealthy person, with an unhealthy diet...expose them to an infection...then refuse to treat them for 10 days...a large proportion of them will get ARDS. In this setting any infection is potentially fatal. If you are old, obese, or have high baseline oxidative stress...any infection can get real bad, real fast.
What is the Crime?
In the 1950s Ancel Keys was trying to make a name for himself. He saw an opportunity with heart disease. He had (stole) a hypothesis - and he ran with it.
But, how did he make it so far? Who were his benefactors? One group was Proctor & Gamble.
In the early 1900s, P&G were in the business of making wax and soap - from animal fat. At some point, animal fat got expensive. So, P&G collaborated with a German who had developed the process of hydrogenation. Here they saw an opportunity to mill cottonseed into oil, and hydrogenate it into something that was 'fatty.' This became a substitute for their wax & soap production, which allowed them to scale.
Eventually, electricity made candle-light obsolete. Which meant that P&G were stuck with a cheap way of making "oil," but no product to put it in. That is until unsaturated fatty acids were hailed (by Ancel et al) as a healthy alternative. P&G repurposed the cottonseed oil into Crisco vegetable oil - without telling people what was in it.
For some people in certain positions (e.g. P&G executives), the idea that their product might cause mass harm and suffering does not even cross their mind.
And, why should it?
The WHO & AHA have promoted PUFAs for decades, and to some extent still do.
Introducing the Grand Jury
For those of you who have no clue what this is about, you would benefit from this twitter thread breaking the players down:
International Grand Jury investigating Crimes Against Humanity has begun!
Supported by the Berlin Corona Committee @CoronaAusschuss, Day 1 Opening Statements were made on February 5th, 2022
Brief 🧵 on crucial background information pic.twitter.com/2ostsnbCZH
— Remnant | MD (@RemnantMd) February 6, 2022
In brief, four German lawyers with experience in consumer protection and medical legal cases formed an investigative committee in July 2020, with the goal of understanding what events had transpired surrounding the SARS-CoV-2 pandemic. They witnessed and broadcast testimony from experts across the globe with a diverse set of knowledge concerned with microbiology, outbreaks, and global interventions.
For a summary of the people interviewed, I discuss in a prior article everyone from Assistant Secretary of Housing and Urban Development, Catherine Austin Fitts to infamous professor of psychology Mattias Desmet and his discussion of Mass Formation.
After the legal team gathered this information, the Corona Investigative Committee collaborated with lawyers around the world in prosecuting governments for violating their constitutional rights. Unfortunately, they met great resistance.
Most recently, they created a sort of Peoples’ Court, in which they have lawyers from several countries collaborating in a model grand jury.
From Wikipedia:
A grand jury is a jury—a group of citizens—empowered by law to conduct legal proceedings, investigate potential criminal conduct, and determine whether criminal charges should be brought. A grand jury may subpoena physical evidence or a person to testify. A grand jury is separate from the courts, which do not preside over its functioning.
The purpose of a grand jury is to accuse persons who may be guilty of a crime. It is a means for lay citizens to participate in the administration of justice. Watergate, for example, had involvement of grand juries. More recently, the prosecution of Purdue Pharma also developed from grand jury investigations.
The juries are ‘grand’ because they are larger than typical jury trials, about 23 jurors. In this case, however, the jurors are the world. Today, tens of thousands of people watched the livestream.
This is what they heard.
Day 2: Historical Background
Before these proceedings began, my goal was to provide highlights of the Day for people to digest. Lo and behold, the first day was about 6 hours long.
So, I shifted to a less unwieldy approach. I’ll be discussing what I believe to be the most valuable pieces of information presented.
You can watch the full proceedings here.
Alex Thomson
Alex Thomson was an officer in Britain’s national intelligence agency, GCHQ. In one of his roles, he served as the transcriber of Russian and German intel. He also has a decorated upbringing, including boarding school and Oxford University. He is also a journalist and writer.
The perspective Alex provides completely floored me. This account is the ultimate historical backdrop to all that has taken place in recent years, and in decades past.
According to Alex, there is a history that lies behind the post-WWII era of health crises which we find ourselves in. Furthermore, the City of London has readied itself for this very moment with efforts that began in the 1870s. From this time, the consuming cartelization of the world began.
Everything that we see unfolding in modern history, points back to the period of 1870. At this time, the British elite instantiated several revolutions concerning the containment of productivity, and prevention of the growth of intellectual property among the native people of the Empire, and its competing nations.
These include revolutions in:
- Education
- Intellectual Property
- Healthcare
- …and Governance
The City of London - the Square Mile
The central node of the Commonwealth is the City of London - henceforth referred to as The City. This square mile at the heart of Greater London, is home to about 9000 people. It also happens to be home to the families of the British Elite.
The City and the Church of England are the only two institutions that have endured every constitutional revolution in the British Isles with their wealth and privileges intact.
The City still has legal status independent of all the boroughs of London. Its privileges date back to the Magna Carta, approximately 1215. Its self-government has never been challenged. Its power has varied across time, but peaked at around the 17th century, during which it challenged the Crown for absolute dominance - thereby having power over a huge portion of the Earth. The City went as far as abolishing the Crown for about a decade.
The British Cabinet Office is the repository of Crown prerogatives. When lay people think of the Crown, they think of the Monarch. In practice, however, this is merely a front. Since 1870, the financiers of political parties are those who pull the levers of the “Crown.”
The City even has a designated seat in Parliament, entitled the Remembrancer. The sitting Monarch of Britain does not have such a privilege.
The model of government which Britain has exported to the Commonwealth includes a Privy Council which governs in the name of the Crown. For example, here is Canadian Prime Minister Justin Trudeau swearing an oath to the Crown & Privy Council:
In Britain, however, Parliament and government departments are merely consulted. There is a veneer of separation between the executive, legislative and judiciary branches of government. As concerns the new Crown and The City, this is merely a show - well documented in the 1873 book entitled The English Constitution.
the dignified parts of government - the show - the attractive parts do have a purpose, but only to attract national support to the working parts behind the scenes.
The City, thus, can be likened to a deep state.
A New Britain
The modern era of Cartelization began around 1870. Up until this point the might of the British Empire and navy was largely unchallenged. The British elite realized they would rapidly face competition from foreign entities.
Starting from the mid-19th century, British foreign policy was primarily concerned with making allies with rivals of the past (France & the Ottomans) in an effort to prevent the future rise of a Russio-German alliance.
Unfortunately for Britian, there was another threat to the West. Namely, the rise of intellectual productivity and the democratization of innovation called the United States.
These changes in the global landscape brought about an existential crisis for Britain. Thus, The City’s trade model had to adjust.
The City adopted a model in which true wealth was to be found in ownership of the mind and body. This model of the world provided the added benefit of preventing the productive class from outproducing and overthrowing their bosses.
Thomson adds:
It is the consistent finding of allied researchers and commentators, that The City and its soft power institutions (BBC, Academia, & Church) continue to regard the battle for the mind as their top priority. Health is regarded merely as a subset of that broader battle.
MINDSPACE
Mindspace is a termed used by The City. It was formalized in the British Cabinet Office’s 2010 publication: Mindspace: Influencing behavior through public policy
MINDSPACE is actually a mnemonic for a checklist. The purpose of this checklist is to guide development of policy to influence behavior.
…we set out nine of the most robust (non-coercive) influences on our behavior, captured in a simple mnemonic - MINDSPACE
- Messenger --| we are heavily influenced by who communicates information
- Incentives -- our responses to incentives are shaped by predictable mental shortcuts such as strongly avoiding losses
- Norms -- we are strongly influenced by what others do
- Defaults -- we „go with the flow‟ of pre-set options
- Salience -- our attention is drawn to what is novel and seems relevant to us
- Priming -- our acts are often influenced by sub-conscious cues
- Affect -- our emotional associations can powerfully shape our actions
- Commitments -- we seek to be consistent with our public promises, and
reciprocate acts- Ego -- we act in ways that make us feel better about ourselves
The British elite regard themselves as the world’s leading power in Mindspace.
The purposes of Mindspace are particularly interesting abroad. The City influences other countries by tricking its own population and the elites of other nations to assume the perspective and narrative of The City in place of their own sovereign interests.
It is not a strategy that is formally taught, but is the credo of leading elite families that run The City, and the modus operandi of the Anglo-American tax-exempt foundations & think-tanks (NGOs) that push the agenda of these families upon Western governments.
All this suggests that our political discourse has veered astray. This perspective of forming public policy is a betrayal of the governmental enterprise, in my estimation.
Here are the Elite in question, at the World Economic Forum, opining on the loss of trust…
The World Economic Forum's Great Narrative Conference: "The good news is the elite across the world trust each other more and more... the bad news is that the majority of people trusted that elite less..." pic.twitter.com/c4I4zlew1p
— James Lindsay, fun (@ConceptualJames) January 21, 2022
On the one hand, culture evolves by the interaction of humans in enterprise. The evolving culture, then, influences legislation.
On the other, you have a governance structure which aims to mold culture by the inaction of public policy. These approaches to governance can be at odds.
As Alex Thomson put it:
If your mindspace is controlled by the Anglosaxon liberal democratic model, then you are going to find a club with self-interest will run the world, even in areas such as healthcare. People will wrongly assume that their best interests are kept at heart.
These MINDSPACE tactics, however, must appear to be legitimate. Otherwise, people get suspicious and resist.
Even if people agree with the behaviour goal, they may object to the means of accomplishing it. The different MINDSPACE effects will attract different levels of controversy.254 There are several factors that determine controversy:
Degree of conscious control. As noted, MINDSPACE effects depend at least partly on the Automatic System. This means that citizens may not fully realise that their behaviour is being changed – or, at least, how it is being changed. Clearly, this opens government up to charges of manipulation. People tend to think that attempts to change their behaviour will be effective if they are simply provided information in an “above board” way - people have a strong dislike of being “tricked”. This dislike has a psychological grounding, but fundamentally it is an issue of trust in government. A lack of conscious control also has implications for consent and freedom of choice. First, it creates a greater need for citizens to approve the use of the behaviour change – perhaps using new forms of democratic engagement. Second, if the effect operates automatically, it may offer little opportunity for citizens to opt- out or choose otherwise; the concept of “choice architecture” is less use here. Any action that may reduce the “right to be wrong” will be very controversial. Of course, some traditional attempts to change behaviour are not explicit (as noted in the „Salience‟ section, some incentives are effectively invisible), and these have attracted controversy. But they rarely attract the charge of „manipulation‟ because they are based on conscious actions to supply and register information, rather than relying on unconscious reactions.
By influencing the cultural institutions of authority, they can capture the peoples’ mind.
Implications for Western Democracy
In the Commonwealth & coastal jurisdictions (e.g. NYC), we are trained by the soft power institutions of The City to think we are in control of our destiny. The strength of The City’s model is the ability to operate at arm's length. To persuade people that what they wanted before, is not what they want now.
Consequently, the MINDSPACE is the most powerful weapon that Britain can wield. The British establishment has not fought fairly since about 1870. Most of the revolutions it hoped to bring about, were all in place by the post-WW2 era.
Thomson continues:
The sovereign power of The City is learned by most by the time they are in boarding school, let alone matriculants of Oxford & Cambrdige. According to this understanding, the rest of the British empire does not have self-determination.
The City owns the population’s body, mind, & soul.
From The City’s perspective, its livestock are not performing in a manner which they deem competitive on the world stage.
Usage of the term livestock is explicit. Up until the 1990s, boarding schools used it to describe the British population. This revolved around the idea that people were cattle, and that their place in the world was under the direction of the Elite.
In effect, the City of London (and its US hub, Wall Street) is battling with the American experiment of self-determination, intellectual productivity and the democratization of innovation. Whilst simultaneously competing with the East.
We are witnessing the evolution of a meta Civil War. Not within a country, but within the western hemisphere. A war which will determine which ethos within the West will rise to contend against the slavish productivity of the East.
I, for one, believe in the American experiment.
Freedom is good for the Soul.
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